Profiling the specific reactivity of the proteome with non-directed activity-based probes
نویسندگان
چکیده
منابع مشابه
Profiling the specific reactivity of the proteome with non-directed activity-based probes.
BACKGROUND The field of proteomics aims to characterize dynamics in protein function on a global level. However, several classes of proteins, in particular low abundance proteins, remain difficult to characterize using standard proteomics technologies. Recently, chemical strategies have emerged that profile classes of proteins based on activity rather than quantity, thereby greatly facilitating...
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ژورنال
عنوان ژورنال: Chemistry & Biology
سال: 2001
ISSN: 1074-5521
DOI: 10.1016/s1074-5521(00)90060-7